Treating Diabetes with Islet Transplantation

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The main cause of is Type 1 diabetes is the failure “Islets”, the insulin-producing cells in the pancreas.

Researchers have been trying to go to the basics and transplant healthy Islets into Diabetic patients. Looks like the transplants are rejected, but a team of Israeli scientists seem to have found a way to successfully transplant healthy islet.

The Israeli team then opted for a new approach, ignoring the rejection of the grafted cells and focusing instead on inflammation caused by the transplant itself. Lewis grafted healthy islets into diabetic mice and treated them with an anti-inflammatory drug called alpha-1-antitrypsin, or AAT. Within months, they discovered three encouraging results:

Source: sfgate

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